Polyacrylic Acid-Protamine Nanoparticles for Scale-Up Experiments in a Microreactor
نویسندگان
چکیده
منابع مشابه
Polyacrylic Acid-Protamine Nanoparticles for Scale-Up Experiments in a Microreactor
Pharmaceutical drug formulations in the nanometer scale received significant interest during the last years as they provide the possibility to stabilize drugs and to transport them directly to their target. Biodegradable self-assembled nanoparticles consisting of protamine and oligonucleotides, so-called “proticles”, have already been successfully developed for different applications [1, 2]. Ho...
متن کاملPile-up glass microreactor.
We made a 'pile-up' microreactor in which ten levels of microchannel circuits were integrated to form a single glass entity. Solutions were distributed to each layer via cylindrical holes with a diameter much larger than that of the microchannel. Fabrication of the pile-up reactor was completed using only conventional photolithography, wet etching and thermal bonding techniques, and no special ...
متن کاملA Scale-up Design Procedure for Rotating Biological Contactors
A scale-up design procedure, based on a new physical mass transfer (PMT) model, whichdescribes the performance, for aerobic rotating biological contactors (RBC’s) is developed. This scale-up procedure can be used to determine the disc surface area needed to prevent an oxygen limitation or to obtain a specific degree of treatment. In contrast to the empirical, and most previous RBC performance m...
متن کاملScale-up Strategies for Membrane-Based Desalination Processes: A Review
Membrane-based technologies have increasingly been chosen in desalination processes, which is evidenced by the increase of large-scale plants constructed in recent years. Indeed, several appropriate strategies should be considered to minimize problems faced during the construction, such as membrane system designs, area requirement, energy requirement, operation and maintenance, and environmenta...
متن کاملBleomycin Loaded Magnetite Nanoparticles Functionalized by Polyacrylic Acid as a New Antitumoral Drug Delivery System
OBJECTIVE To prepare, characterize, and analyze the release behavior of bleomycin-loaded magnetite nanoparticles (BLM-MNPs) coated with polyacrylic acid (PAA) as a new drug delivery system that can be specifically distributed in the tumor site. METHODS BLM-MNPs coated with PAA were prepared using a solvothermal approach. The particles were characterized using scanning electron microscope (SEM...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2010
ISSN: 0036-8709,2218-0532
DOI: 10.3797/scipharm.cespt.8.pnm17